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晚期糖基化终末产物AGEs
  • 产品货号:
    BN40025
  • 中文名称:
    晚期糖基化终末产物AGEs
  • 英文名称:
    AGEs
  • 别名:
    AGEs Protein
  • 货号

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  • BN40025-10mg

    10mg

    ¥1640.00

  • BN40025-50mg

    50mg

    ¥5530.00

性状:Lyophilized or Liquid

储存液:PBS (pH=7.4).

研究领域:

                Cardiovascular > Blood > Serum Proteins

                Developmental Biology > Lineage specification > Endoderm

                Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Signal transduction proteins ELISA kits

                Metabolism > Types of disease > Metabolic disorders

                Signal Transduction > Metabolism > Lipid metabolism

                Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones

                Stem Cells > Lineage Markers > Endoderm

亚细胞定位 :Secreted.

组织特异性:Plasma.

翻译后修饰:

                   Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.

                   Glycated in diabetic patients.

                   Phosphorylation sites are present in the extracelllular medium.

                   Acetylated on Lys-223 by acetylsalicylic acid.

疾病:

Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased 

affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

相似性:Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains.

活性:Yes

序列:Purified native protein

纯度:>95% as determined by SDS-PAGE

内毒素:Not analyzed

功能:

Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function 

is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Storage: Store at –20℃ for one year. When dissolved, avoid repeated freeze/thaw cycles.