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晚期糖基化终末产物AGEs
  • 产品货号:
    BN40025
  • 中文名称:
    晚期糖基化终末产物AGEs
  • 英文名称:
    AGEs
  • 别名:
    AGEs Protein
  • 货号

    产品规格

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  • BN40025-10mg

    10mg

    ¥1640.00

  • BN40025-50mg

    50mg

    ¥5530.00

性状:Lyophilized or Liquid

储存液:PBS (pH=7.4).

研究领域:

                Cardiovascular > Blood > Serum Proteins

                Developmental Biology > Lineage specification > Endoderm

                Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Signal transduction proteins ELISA kits

                Metabolism > Types of disease > Metabolic disorders

                Signal Transduction > Metabolism > Lipid metabolism

                Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones

                Stem Cells > Lineage Markers > Endoderm

亚细胞定位 :Secreted.

组织特异性Plasma.

翻译后修饰

                   Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.

                   Glycated in diabetic patients.

                   Phosphorylation sites are present in the extracelllular medium.

                   Acetylated on Lys-223 by acetylsalicylic acid.

疾病

Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased 

affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

相似性Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains.

活性Yes

序列Purified native protein

纯度>95% as determined by SDS-PAGE

内毒素Not analyzed

功能

Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function 

is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Storage: Store at –20℃ for one year. When dissolved, avoid repeated freeze/thaw cycles.