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小鼠C-肽抗体
  • 产品货号：
    BN40764R
  • 中文名称：
    小鼠C-肽抗体
  • 英文名称：
    Rabbit anti-C Peptide (mouse) Polyclonal antibody

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    产品规格

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  • BN40764R-100ul

    100ul

    ¥2360.00

    交叉反应：Rat(predicted:Mouse) 推荐应用：IHC-P,IHC-F,ICC,IF

  • BN40764R-200ul

    200ul

    ¥3490.00

    交叉反应：Rat(predicted:Mouse) 推荐应用：IHC-P,IHC-F,ICC,IF

英文名称C Peptide (mouse)
中文名称小鼠C-肽抗体
别    名proinsulin precursor; Hyperproinsulinemia; INS; Insulin Precursor; IRDN; Proinsulin; Propeptide; C-Peptide; INS2_MOUSE.  
研究领域肿瘤  细胞生物  信号转导  生长因子和激素  糖尿病  细胞因子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Rat,  (predicted: Mouse, )
产品应用IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量3kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from mouse C Peptide:57-87/110 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍C Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C Peptide are produced. C peptide is released into the blood stream in equal amounts to insulin. A test of C peptide levels will show how much insulin the body is making. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Function:
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Subunit:
Heterodimer of a B chain and an A chain linked by two disulfide bonds.

Subcellular Location:
Secreted.

Similarity:
Belongs to the insulin family.

SWISS:
P01326

Gene ID:
16334

Database links:

Entrez Gene: 3630 Human

Entrez Gene: 16334 Mouse

Omim: 176730 Human

SwissProt: P01308 Human

SwissProt: P01326 Mouse

Unigene: 272259 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

C肽是胰岛β细胞的分泌产物，与大、小鼠有部分交叉，它与胰岛素有一个共同的前体——胰岛素原
C肽是连接肽，因为最初它是连接A、B两条链的中间段，胰岛素原分解后才能独立存在，它也能从细胞释放到血液中。因此，从胰岛细胞分泌入血的主要成分有两种，一种是人们所熟悉的胰岛素，另一种就是C肽。
近年来，随着深入的研究，发现C肽是具有生物学活性的。并且，这种生物学活性对于延缓糖尿病慢性并发症的发生和发展可能具有重要的作用.

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