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G2期/S期应答相关蛋白1抗体
  • 产品货号:
    BN40823R
  • 中文名称:
    G2期/S期应答相关蛋白1抗体
  • 英文名称:
    Rabbit anti-GTSE-1 Polyclonal antibody
  • 货号

    产品规格

    售价

    备注

  • BN40823R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse(predicted:Rat,Chicken,Pig,Cow) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN40823R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse(predicted:Rat,Chicken,Pig,Cow) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

英文名称GTSE-1
中文名称G2期/S期应答相关蛋白1抗体
别    名G2 and S phase-expressed protein 1; B99; B99 homolog; G 2 and S phase expressed 1; G two S phase expressed protein 1; GTSE 1; GTSE-1; GTSE1; GTSE1_HUMAN.  
研究领域细胞生物  免疫学  细胞周期蛋白  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Chicken, Pig, Cow, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量77kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GTSE-1:651-739/739 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]

Function:
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.

Subcellular Location:
Cytoplasm, cytoskeleton. Note=Associated with microtubules.

Post-translational modifications:
Phosphorylated in mitosis.

Similarity:
Sequence=CAQ09324.2; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAQ10552.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.

SWISS:
Q9NYZ3

Gene ID:
51512

Database links:

Entrez Gene: 51512 Human

Omim: 607477 Human

SwissProt: Q9NYZ3 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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